On June 14th 2025, Israeli emergency services confirmed three fatalities and numerous injuries caused by Iran’s Operation True Promise III attack against central Israel. The attack, part of Iran’s response for Israeli strikes against their nuclear and military infrastructure earlier in 2025, marked a significant escalation of their ongoing conflict, according to several sources, such as The Guardian, Wsj.com, Wikipedia etc.
Casualties and Human Impact
The first deaths were reported early Saturday in Rishon LeZion, just south of Tel Aviv. One victim died due to structural collapse; two succumbed to injuries at hospital before another one succumbed on their way. A third Israeli casualty–one killed during Friday night’s bombardment–was declared deceased at Rabin Medical Center east of Tel Aviv (Wall Street Journal.com).
Additionally, several dozen people were injured from minor to severe injuries; three-month-old baby miraculously saved after spending two hours trapped beneath debris was among them and miraculously transported back to safety after two hours in a safe room wsj.com +2 whilst others required medical treatment en.wikipedia org +2.
Israeli media reported widespread destruction to private homes, apartment complexes, and infrastructure after an unexpected missile strike by Syria on Tuesday (en.wikipedia.org, business-standard.com and i24news.tv).
Defense and Interceptions
Despite Iran’s aggressive launch–over 150 ballistic missiles and 100 drones–Israel’s air defense systems supported by U.S. interceptors managed to neutralize most of Iran’s threat through interceptors deployed from U.S. military aircraft. To combat Iran, Israel used air defense systems designed by Boeing that included missile interceptors. They managed this feat thanks to strategic cooperation. At timesofindia.indiatimes.com/ +11 and business-standard.com+11 for both websites +11 both contained articles by timeofindia/indiatimes/ +11. wikipedia/en /w_init
However, approximately 25% managed to break through defences, striking residential areas in Tel Aviv, Ramat Gan and Rishon LeZion and causing extensive structural damage en.wikipedia.org/11 and +11.
Local emergency services worked through the night to rescue trapped residents. Footage captured scenes of desperation and urgency as rescue workers pulled survivors from debris-strewn apartments, according to timesofisrael.com.
Damage Assessment
According to damage assessment reports, multiple apartment blocks suffered collapsed walls and broken windows. Ramat Gan was forced to evacuate several buildings due to structural instability while Tel Aviv suburban zones saw broken windows, cracked facades, damaged vehicles lining streets as well as at least one partially collapsed apartment building prompting intensive search-and-rescue responses and more than 15 evacuation orders from authorities (The Times (UK), TimesofIsrael.com (Israel) and NY Post) for rescue missions triggered an intensive response system.
Wider Context
Iran launched its most significant direct military attack since April 2024 with this attack and marks an evolution from proxy engagements towards overt confrontation. (Sources for information are listed at Wikipedia for each event.)
Operation Rising Lion was an Israeli air offensive which targeted over 100 Iranian sites including nuclear facilities such as Natanz and missile launch pads; senior IRGC commanders and nuclear scientists reportedly died as part of this operation (Reuters/Times of India/Guardian/Times.co.uk/Page1/897477841).
Iran launched multiple waves of its retaliatory barrage–called True Promise III–to overwhelm Israeli defences, inflicting casualties and injuries across six waves. One wave alone caused fatalities. (Wikipedia)
International and Domestic Response
Prime Minister Netanyahu strongly condemned the attack and stressed Israel’s right to defend itself, warning of potential further Iranian aggression leading to “stronger Israeli response”. (Wikipedia).
Concurrently, authorities throughout Israel strengthened air defenses and activated emergency reception centers.

Global responses were swift. U.S. and Western governments voiced support for Israel’s right to defend itself while calling for restraint to avert wider war, whilst warning of possible dire repercussions for all involved parties. enwikipedia.org
Meanwhile, the UN Security Council issued an appeal for de-escalation, signed by leaders from UK, France, Egypt, Saudi Arabia and Jordan (APNews.com). What’s Next
Future Military Exchanges Possible: Both parties have indicated an intent for more military exchanges, raising fears of an expanded regional conflict.

Humanitarian Impact: Displaced civilians now require shelter, medical care and psychological support services.

Diplomatic hurdles: Diplomatic efforts between Iran and the U.S. to revive nuclear talks have effectively failed due to deepening hostilities; Business Standard reports this.
Bottom Line: Iran’s missile barrage marked a sudden and deadly escalation in direct combat with Israel. Following three confirmed casualties and widespread destruction, global concern rose dramatically as to which side will commit to restraint or escalate in retaliatory measures against each other further.